Developing and evaluating complex interventions: the new Medical Research Council guidance

This document provides guidance on the development, evaluation and implementation of complex interventions
to improve health. It updates the advice provided in the 2000 MRC Framework for the Development and Evaluation of RCTs for Complex Interventions to Improve Health, taking account of the valuable experience that has accumulated since then, and extending the coverage in the guidance of non-experimental methods, and of complex interventions outside the health service. It is intended to help researchers to choose appropriate methods, research funders to understand the constraints on evaluation design, and users of evaluation to weigh up the available evidence in the light of these methodological and practical constraints. Box 1 summarises the main elements of the process, and the key questions that researchers should ask themselves as they work through it.

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