This paper explores the differing opinions of various stakeholders in relation to trypanosomiasis, a widespread and potentially fatal disease spread by tsetse flies which affects both humans and animals. It is an important time to examine this issue as human population growth and other factors have led to migration into new areas which are populated by tsetse flies, and this may affect disease levels. This means that there is a greater risk to people and their livestock, and opinions on the best way to manage the disease are deeply divided. Cross sector working hasn’t been used historically, but breaking down the barriers between social scientists, natural scientists and the expertise of the community could lead to better disease management.